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Retinoblastoma Protein (Rb) Antikörper (AA 586-615)

Rb Protein Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032465
  • Target Alle Retinoblastoma Protein (Rb) (Rb Protein) Antikörper anzeigen
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Bindungsspezifität
    • 15
    • 14
    • 14
    • 14
    • 14
    • 9
    • 9
    • 8
    • 8
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 586-615
    Reaktivität
    • 174
    • 71
    • 56
    • 8
    • 8
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 151
    • 24
    Kaninchen
    Klonalität
    • 149
    • 26
    Polyklonal
    Konjugat
    • 85
    • 17
    • 10
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    Dieser Retinoblastoma Protein (Rb) Antikörper ist unkonjugiert
    Applikation
    • 89
    • 88
    • 83
    • 28
    • 26
    • 14
    • 14
    • 9
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Antigen affinity purified
    Immunogen
    A portion of amino acids 586-615 from the human protein was used as the immunogen for this Rb antibody.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product Rb Protein Primärantikörper
  • Applikationshinweise
    Titration of the Rb antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:1000,Immunofluorescence: 1:10-1:50,IHC (Paraffin): 1:10-1:50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In 1X PBS, pH 7.4, with 0.09 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot the Rb antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
  • Target
    Retinoblastoma Protein (Rb) (Rb Protein) (Retinoblastoma Protein (Rb Protein))
    Andere Bezeichnung
    Rb (Retinoblastoma) (Rb Protein Produkte)
    Hintergrund
    The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in many types of cancer. One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins. Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer. Retinoblastoma (Rb) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral.
    UniProt
    P06400
    Pathways
    Mitotic G1-G1/S Phases
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