Nidogen Antikörper

Produktnummer ABIN7881810

Dieser Ratte Monoklonal Antikörper detektiert spezifisch Nidogen in ELISA. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für Nidogen Antikörper (ABIN7881810)

Target: Nidogen (NID)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Nidogen Antikörper ist unkonjugiert

Applikation: ELISA

Klon: ELM1

Produktdetails anti-Nidogen Antikörper

Verwendungszweck: Nidogen Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: A murine EHS laminin preparation was used as the immunogen for the Nidogen antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Nidogen antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Nidogen antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Nidogen

Target: Nidogen (NID)

Andere Bezeichnung: Nidogen

Hintergrund: Entactin/Nidogen is a ubiquitous multi-domain basement membrane protein. Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation. This MAb does not cross-react with other basement membrane components or fibronectin.

UniProt: P10493