Nidogen Antikörper

Produktnummer ABIN7861825

Der Ratte Monoklonal anti-Nidogen Antikörper (Klon ELM1) (ABIN7861825) detektiert spezifisch Nidogen in ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Meerschweinchen.

Kurzübersicht für Nidogen Antikörper (ABIN7861825)

Target: Nidogen (NID)

Reaktivität: Maus, Meerschweinchen

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Nidogen Antikörper ist unkonjugiert

Applikation: ELISA

Klon: ELM1

Produktdetails anti-Nidogen Antikörper

Verwendungszweck: Nidogen / Entactin Antibody

Spezifität: It reacts with the intact (150 kDa) nidogen as well as its proteolytic fragments of 135 kDa, 110 kDa, 100 kDa, and 80 kDa. This MAb does not cross-react with other basement membrane components or fibronectin. Entactin/Nidogen is a ubiquitous multi-domain basement membrane protein. Basement membranes are the earliest extracellular matrices produced during embryogenesis. They are synthesized and incorporated into the supramolecular architecture of several components, including laminins, Collagen IV, Nidogen and proteoglycans. Nidogen/Entactin, a sulfated glycoprotein, acts as a link between the extracellular matrix molecules Laminin 1 and Collagen Type IV, and thereby participates in the assembly of basement membranes. Nidogen is synthesized and secreted in primary and established mesenchymal peritubular cells and myoepithelial cells, and it affects adhesion of peritubular cells in an autocrine manner. Nidogen is expressed during embryonic and fetal development exclusively in fully developed basement membranes of the ectoderm and is not expressed in the developing endodermal basement membrane or in membranes disrupted during mesoderm formation.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Murine EHS laminin preparation

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Nidogen

Target: Nidogen (NID)

Andere Bezeichnung: Nidogen

Hintergrund:

Nid1, Ent, Entactin 1, NID-1, Nidogen-1,

Mouse kidney or eye tissue.

Molekulargewicht: 100|105|110|135|and 80kDa