Rekombinanter KRT6A Antikörper

Produktnummer ABIN7881412

Der Kaninchen Monoklonal anti-KRT6A Antikörper wird verwendet zum Nachweis von KRT6A in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter KRT6A Antikörper (ABIN7881412)

Target: KRT6A (Keratin 6A (KRT6A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KRT6A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: KRT6-8120R

Produktdetails anti-KRT6A Antikörper

Verwendungszweck: Cytokeratin 6A Antibody

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment of human KRT6 protein was used as the immunogen for the Cytokeratin 6A antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cytokeratin 6A antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Cytokeratin 6A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Andere Bezeichnung: Cytokeratin 6A

Hintergrund: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

UniProt: P02538