KRT6A Antikörper (AA 253-352)

Produktnummer ABIN7193708

Produktdetails anti-KRT6A Antikörper

Target: KRT6A (Keratin 6A (KRT6A))

Bindungsspezifität: AA 253-352

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT6A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human KRT6A (AA: 253-352) expressed in E. coli.

Klon: 7E3D1

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: WB:1:500 - 1:2000, ICC:1:200 - 1:1000, FCM:1:200 - 1:400, ELISA:1:10000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Andere Bezeichnung: KRT6A (KRT6A Produkte)

Synonyme: CK6A antikoerper, CK6C antikoerper, CK6D antikoerper, K6A antikoerper, K6C antikoerper, K6D antikoerper, KRT6C antikoerper, KRT6D antikoerper, 2310016L08Rik antikoerper, Krt2-6a antikoerper, Krt2-6c antikoerper, MK6a antikoerper, mK6[a] antikoerper, CK-6A antikoerper, Krt6a antikoerper, KRT6A antikoerper, keratin 6A antikoerper, similar to keratin complex 2, basic, gene 6a antikoerper, keratin, type II cytoskeletal 6A antikoerper, KRT6A antikoerper, Krt6a antikoerper, LOC683313 antikoerper, LOC101112304 antikoerper

Hintergrund:

Description: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified, the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Aliases: KRT6A, K6A, K6C, K6D, PC3, CK6C, CK6D, CK-6C, CK-6E, KRT6C, KRT6D

Molekulargewicht: 60 kDa

Gen-ID: 3853