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HLA-ABC Antikörper

Der Maus Monoklonal anti-HLA-ABC Antikörper (Klon Bra-23-9) (ABIN7881088) detektiert spezifisch HLA-ABC in FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN7881088
312,40 €
Zzgl. Versandkosten 20,00 € und MwSt
20 μg
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen

Kurzübersicht für HLA-ABC Antikörper (ABIN7881088)

Target

Alle HLA-ABC Antikörper anzeigen
HLA-ABC

Reaktivität

  • 92
  • 28
  • 21
  • 19
  • 17
  • 13
  • 13
  • 13
  • 12
  • 11
  • 7
  • 7
  • 6
  • 6
  • 2
  • 2
  • 1
Human

Wirt

  • 70
  • 18
  • 4
  • 1
Maus

Klonalität

  • 83
  • 9
Monoklonal

Konjugat

  • 47
  • 7
  • 7
  • 7
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HLA-ABC Antikörper ist unkonjugiert

Applikation

  • 67
  • 19
  • 17
  • 16
  • 15
  • 15
  • 10
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)

Klon

Bra-23-9
  • Verwendungszweck

    HLA-ABC Antibody

    Aufreinigung

    Protein A/G affinity

    Immunogen

    Human REH cells (a pre-B leukaemia cell line) was used as the immunogen for the HLA-ABC antibody.

    Isotyp

    IgG2a, kappa
  • Applikationshinweise

    Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.2 mg/mL

    Buffer

    0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the HLA-ABC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • Target

    HLA-ABC

    Andere Bezeichnung

    HLA-ABC

    Hintergrund

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Immunoprecipitation of lactoperoxidase radioiodinated cell surface proteins and surface sialoglycoproteins radiolabeled by sodium metaperiodate/tritiated sodium borohydride technique confirmed the structure gp44,p12 (consisting of a 44 kDa glycopeptide linked with a non-glycosylated 12 kDa peptide) typical for MHC class I antigen(s) as a structure recognized by Bra23/9. Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

    UniProt

    P01889

    Pathways

    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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