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HLA-ABC Antikörper

GMP Grade HLA-ABC Reaktivität: Human, Pavian, Cynomolgus, Rhesusaffen FACS Wirt: Maus Monoclonal W6-32 unconjugated
Produktnummer ABIN5067844
  • Target Alle HLA-ABC Antikörper anzeigen
    HLA-ABC
    Reaktivität
    • 71
    • 23
    • 15
    • 13
    • 13
    • 11
    • 11
    • 11
    • 8
    • 7
    • 7
    • 6
    • 1
    • 1
    • 1
    Human, Pavian, Cynomolgus, Rhesusaffen
    Wirt
    • 60
    • 9
    • 3
    Maus
    Klonalität
    • 62
    • 9
    Monoklonal
    Konjugat
    • 33
    • 8
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HLA-ABC Antikörper ist unkonjugiert
    Applikation
    • 56
    • 19
    • 18
    • 11
    • 10
    • 10
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Produktmerkmale
    Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
    Aufreinigung
    Purified
    Reinheit
    >95 %
    Güteklasse
    GMP Grade
    Immunogen
    Human Leukocytes
    Klon
    W6-32
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product HLA-ABC Primärantikörper
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
  • Target
    HLA-ABC
    Andere Bezeichnung
    HLA-ABC (HLA-ABC Produkte)
    Synonyme
    HLAA antikoerper, major histocompatibility complex, class I, A antikoerper, HLA-A antikoerper
    Hintergrund
    Clone W6/32 recognizes a cell surface 45 kD non-polymorphic epitope protein shared among products of the HLA-A, B, and C loci. HLA class I antigen associated with beta 2-microglobulin are expressed by all human nucleated cells and HLA-Class I down regulation occurs frequently in many cancers which might adversely affect the clinical course of cancer and the outcome of T-cell-based immunotherapy. HLA-Class I present specific foreign antigen to CD8+ T cells which play central role against infection, tumor and also generation of autoimmune diseases.
    Pathways
    T-Zell Rezeptor Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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