Ghrelin Antikörper

Produktnummer ABIN7880867

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Ghrelin in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Ghrelin Antikörper (ABIN7880867)

Target: Ghrelin (GHRL)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ghrelin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Ghrelin Antikörper

Verwendungszweck: Ghrelin Antibody / GHRL

Aufreinigung: Antigen affinity purified

Immunogen: the Ghrelin antibody can be stored for up to one month at 4oC. For long-term

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Ghrelin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Ghrelin

Target: Ghrelin (GHRL)

Andere Bezeichnung: Ghrelin

Hintergrund: This gene encodes the ghrelin-obestatin preproprotein that is cleaved to yield two peptides, ghrelin and obestatin. Ghrelin is a powerful appetite stimulant and plays an important role in energy homeostasis. Its secretion is initiated when the stomach is empty, whereupon it binds to the growth hormone secretagogue receptor in the hypothalamus which results in the secretion of growth hormone (somatotropin). Ghrelin is thought to regulate multiple activities, including hunger, reward perception via the mesolimbic pathway, gastric acid secretion, gastrointestinal motility, and pancreatic glucose-stimulated insulin secretion. It was initially proposed that obestatin plays an opposing role to ghrelin by promoting satiety and thus decreasing food intake, but this action is still debated. Recent reports suggest multiple metabolic roles for obestatin, including regulating adipocyte function and glucose metabolism. Alternative splicing results in multiple transcript variants. In addition, antisense transcripts for this gene have been identified and may potentially regulate ghrelin-obestatin preproprotein expression.,Amino acids QRKESKKPPAKLQPR from the human protein were used as the immunogen for the Ghrelin antibody.,After reconstitution

UniProt: Q9UBU3

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Negative Regulation of Hormone Secretion, Synaptic Membrane, Feeding Behaviour