F11R Antikörper

Produktnummer ABIN7880760

Der Kaninchen Polyklonal anti-F11R Antikörper wird verwendet zum Nachweis von F11R in Proben von Human. Er wurde validiert für WB, FACS und IF.

Kurzübersicht für F11R Antikörper (ABIN7880760)

Target: F11R (F11 Receptor (F11R))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F11R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-F11R Antikörper

Verwendungszweck: F11R Antibody / JAM-A

Sequenz: RVEWKFDQGD TTRLVCYNNK

Aufreinigung: Affinity purified

Immunogen: Amino acids RVEWKFDQGDTTRLVCYNNK from the human protein were used as the immunogen for the F11R antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the F11R antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the F11R antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu F11R

Target: F11R (F11 Receptor (F11R))

Andere Bezeichnung: F11R

Hintergrund: Junctional adhesion molecule A is a protein that in humans is encoded by the F11R gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization