Cyclin E2 Antikörper

Produktnummer ABIN7880528

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Cyclin E2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Cyclin E2 Antikörper (ABIN7880528)

Target: Cyclin E2 (CCNE2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Cyclin E2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: EDB-3

Produktdetails anti-Cyclin E2 Antikörper

Verwendungszweck: CCNE2 Antibody / Cyclin E2

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human Cyclin E2 / CCNE2 was used as the immunogen for the CCNE2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CCNE2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the CCNE2 antibody at -20oC.

Details zu Cyclin E2

Target: Cyclin E2 (CCNE2)

Andere Bezeichnung: CCNE2

Hintergrund: G1/S-specific cyclin-E2' belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [RefSeq]

UniProt: O96020

Pathways: Zellzyklus, Mitotic G1-G1/S Phases