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Cyclin E2 Antikörper (CCNE2) C-Term Primary Antibody

CCNE2 Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN129714
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle Cyclin E2 (CCNE2) Antikörper anzeigen
    Cyclin E2 (CCNE2)
    Bindungsspezifität
    • 15
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 58
    • 27
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 56
    • 2
    • 2
    Kaninchen
    Klonalität
    • 50
    • 10
    Polyklonal
    Konjugat
    • 37
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cyclin E2 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 19
    • 16
    • 15
    • 14
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Human
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids at the of the Cyclin E2 protein.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 50 kDa in size corresponding to Cyclin E2 protein by western blotting in the appropriate cell lysate or extract.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.17 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Target
    Cyclin E2 (CCNE2)
    Andere Bezeichnung
    Cyclin E2 (CCNE2 Produkte)
    Synonyme
    ccne2, MGC53684, MGC132360, cb165, sb:cb165, zgc:86724, CCNE2, cyce2, CYCE2, cyclin E2, cyclin E2 L homeolog, cyclin E1 L homeolog, CCNE2, ccne2.L, ccne2, ccne1.L, Ccne2
    Hintergrund
    This antibody is designed, produced, and is suitable for Cancer, Immunology and Nuclear Signaling research. Cyclin E was first identified by its ability to rescue growth of yeast deficient in G1 Cyclins, indicating a role in G1 or G1/S transitions.  Over-expression of Cyclin E has been observed in a variety of human tumors. Multiple isoforms of Cyclin E are expressed in tumors but not in normal tissues, suggesting a post-transcriptional regulation of Cyclin E.  Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27Kip1 and p21Cip1.  The catalytic activity associated with Cyclin E2 complexes is cell cycle regulated and peaks at the G1/S transition.  Unlike Cyclin E1, which is expressed in most proliferating normal and tumor cells, Cyclin E2 levels were low to undetectable in non-transformed cells and increased significantly in tumor-derived cells.
    Synonyms: G1/S-specific cyclin-E2
    Gen-ID
    12448, 3769612
    UniProt
    Q9Z238
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases
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