Ku70 + Ku80 Antikörper (CF®488A)
Kurzübersicht für Ku70 + Ku80 Antikörper (CF®488A) (ABIN7880388)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Ku70 + Ku80 Antibody
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the Ku70 + Ku80 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store the Ku70 + Ku80 antibody at 2-8oC, protected from light.
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- Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
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Andere Bezeichnung
- Ku70 + Ku80
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Hintergrund
- Recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Target
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