Ku70 + Ku80 Antikörper (PE)

Produktnummer ABIN3026514

Der Maus Monoklonal anti-Ku70 + Ku80 Antikörper wird verwendet zum Nachweis von Ku70 + Ku80 in Proben von Human, Primate, Huhn und Ratte. Er wurde validiert für IF und FACS.

Kurzübersicht für Ku70 + Ku80 Antikörper (PE) (ABIN3026514)

Target: Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))

Reaktivität: Human, Primate, Huhn, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Ku70 + Ku80 Antikörper ist konjugiert mit PE

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: KU729

Produktdetails anti-Ku70 + Ku80 Antikörper (PE)

Verwendungszweck: Ku70 + Ku80 Antibody PE Conjugate

Keine Kreuzreaktivität: Maus, Ratte (Rattus), Huhn

Produktmerkmale: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Aufreinigung: Protein G affinity chromatography

Immunogen: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ku70 + Ku80 antibody to be titered up or down for optimal performance.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the Ku70 + Ku80 antibody at 2-8oC. Conjugate is light sensitive, store in the dark.

Details zu Ku70 + Ku80

Target: Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))

Andere Bezeichnung: Ku70 + Ku80

Hintergrund: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.