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Ku70 + Ku80 Antikörper

KU80 Reaktivität: Human, Primate FACS, IF, ICC Wirt: Maus Monoclonal KU729 unconjugated
Produktnummer ABIN6251789
  • Target Alle Ku70 + Ku80 (KU80) Produkte
    Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
    Reaktivität
    Human, Primate
    Wirt
    • 2
    • 1
    Maus
    Klonalität
    • 2
    • 1
    Monoklonal
    Konjugat
    • 2
    • 1
    Dieser Ku70 + Ku80 Antikörper ist unkonjugiert
    Applikation
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Does not react with mouse, rat, chicken
    Aufreinigung
    Protein G purified monoclonal antibody
    Immunogen
    Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.
    Klon
    KU729
    Isotyp
    IgG1 kappa
  • Applikationshinweise
    Flow cytometry: 0.5-1 μg/10e6 cells

    IF: 0.5-1.0 μg/mL

    Immunocytochemistry (Acetone-fixed cells): 0.25-0.5 μg/mL for 30 minutes at RT

    The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ku70 + Ku80 antibody to be titered up or down for optimal performance.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.2 mg/mL
    Buffer
    PBS with 0.1 mg/mL BSA and 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Aliquot and Store at -20C. Avoid freez-thaw cycles.
  • Target
    Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))
    Andere Bezeichnung
    Ku70 + Ku80 (KU80 Produkte)
    Hintergrund
    This antibody recognizes a dimer of two proteins of 70  kDa (Ku70) and ~80  kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460  kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
    Gen-ID
    2547
    UniProt
    Q6FG89
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