CD46 Antikörper

Produktnummer ABIN7880328

Der Kaninchen Monoklonal anti-CD46 Antikörper wird verwendet zum Nachweis von CD46 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für CD46 Antikörper (ABIN7880328)

Target: CD46

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: AEI-3

Produktdetails anti-CD46 Antikörper

Verwendungszweck: CD46 Antibody

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human CD46 was used as the immunogen for the CD46 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD46 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the CD46 antibody at -20oC.

Details zu CD46

Target: CD46

Andere Bezeichnung: CD46

Hintergrund: The protein encoded by the CD46 gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. [RefSeq]

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization