alpha 2 Macroglobulin Antikörper

Produktnummer ABIN7879957

Der Kaninchen Monoklonal anti-alpha 2 Macroglobulin Antikörper (Klon ABAO-1) (ABIN7879957) detektiert spezifisch alpha 2 Macroglobulin in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für alpha 2 Macroglobulin Antikörper (ABIN7879957)

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: ABAO-1

Produktdetails anti-alpha 2 Macroglobulin Antikörper

Verwendungszweck: Alpha-2-macroglobulin Antibody / A2M

Aufreinigung: Affinity purified

Immunogen: A synthetic peptide specific to human A2M / Alpha 2 Macroglobulin was used as the immunogen for the Alpha-2-macroglobulin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Alpha-2-macroglobulin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store the Alpha-2-macroglobulin antibody at -20oC.

Details zu alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Andere Bezeichnung: Alpha-2-macroglobulin

Hintergrund: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [RefSeq]

UniProt: P01023

Pathways: Lipid Metabolism