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alpha 2 Macroglobulin Antikörper

A2M Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Monoclonal unconjugated
Produktnummer ABIN7265558
  • Target Alle alpha 2 Macroglobulin (A2M) Antikörper anzeigen
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    Reaktivität
    • 108
    • 23
    • 20
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 106
    • 18
    • 15
    • 6
    • 1
    • 1
    Kaninchen
    Klonalität
    • 124
    • 21
    Monoklonal
    Konjugat
    • 77
    • 21
    • 14
    • 9
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert
    Applikation
    • 90
    • 59
    • 37
    • 19
    • 14
    • 9
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Verwendungszweck
    Alpha-2-Macroglobulin (A2M) Rabbit mAb
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Monoclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthesized peptide derived from human Alpha-2-Macroglobulin (Alpha-2-Macroglobulin (A2M))
    Isotyp
    IgG
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  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
    Andere Bezeichnung
    A2M (A2M Produkte)
    Synonyme
    A2MD antikoerper, CPAMD5 antikoerper, FWP007 antikoerper, S863-7 antikoerper, A2MAC1 antikoerper, A2m1 antikoerper, A2maa antikoerper, Mam antikoerper, A2mp antikoerper, A2M antikoerper, LOC733429 antikoerper, endod antikoerper, cpamd5 antikoerper, fwp007 antikoerper, s863-7 antikoerper, a2mb antikoerper, endodermin antikoerper, Alpha-2-M antikoerper, alpha-2-macroglobulin antikoerper, pregnancy-zone protein L homeolog antikoerper, alpha-2-macroglobulin S homeolog antikoerper, pregnancy zone protein antikoerper, alpha-2-macroglobulin-like antikoerper, A2M antikoerper, A2m antikoerper, LOC477699 antikoerper, pzp.L antikoerper, AZL_c00450 antikoerper, LOC100349077 antikoerper, a2m antikoerper, LOC100061656 antikoerper, LOC100090399 antikoerper, a2m.S antikoerper, LOC100469973 antikoerper, LOC100595735 antikoerper, PZP antikoerper, LOC100353095 antikoerper, LOC101122940 antikoerper, LOC101801552 antikoerper, LOC100911545 antikoerper
    Hintergrund
    The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016],A2MD, CPAMD5, FWP007, S863-7,Blood,Blood_Serum Proteins,Cardiovascular,Cell Biology & Developmental Biology,Ubiquitin,A2M
    Molekulargewicht
    163kDa
    Gen-ID
    2
    UniProt
    P01023
    Pathways
    Lipid Metabolism
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