MSK1 Antikörper (pSer376)
Kurzübersicht für MSK1 Antikörper (pSer376) (ABIN7879734)
Target
Alle MSK1 (RPS6KA5) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer376
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Verwendungszweck
- Phospho-MSK1 Antibody (pS376)
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Aufreinigung
- Affinity purified
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Immunogen
- A synthetic peptide specific to human MSK1 / RPS6KA5 (surrounding pS376) was used as the immunogen for the phospho-MSK1 antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the phospho-MSK1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store the phospho-MSK1 antibody at -20oC.
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- MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
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Andere Bezeichnung
- MSK1
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Hintergrund
- Mitogen and stress activated protein kinase 1,' also called RPS6KA5, is a serine/threonine-protein kinase that is required for the mitogen or stress-induced phosphorylation of the transcription factors CREB1 and ATF1 and for the regulation of the transcription factors RELA, STAT3 and ETV1/ER81, and that contributes to gene activation by histone phosphorylation and functions in the regulation of inflammatory genes. Phosphorylates CREB1 and ATF1 in response to mitogenic or stress stimuli such as UV-C irradiation, epidermal growth factor (EGF) and anisomycin. [UniProt]
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UniProt
- O75582
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Pathways
- MAPK Signalweg, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
Target
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