Rekombinanter ACTH Antikörper (N-Term)
Kurzübersicht für Rekombinanter ACTH Antikörper (N-Term) (ABIN7879555)
Target
Alle ACTH Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- N-Term
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Verwendungszweck
- Recombinant ACTH Antibody (Synacthen)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant protein fragment from the N-terminal region of human ACTH was used as the immunogen for the recombinant ACTH antibody.
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Isotyp
- IgG1, kappa
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Applikationshinweise
- Optimal dilution of the recombinant ACTH antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the recombinant ACTH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- ACTH (Adrenocorticotropic hormone (ACTH))
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Andere Bezeichnung
- ACTH
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Hintergrund
- ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH), does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.
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UniProt
- P01189
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Pathways
- Metabolism of Steroid Hormones and Vitamin D, Peptide Hormone Metabolism, Hormone Activity
Target
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