Der Maus Monoklonal anti-ACTH Antikörper wird verwendet zum Nachweis von ACTH in Proben von Human, Ratte und Maus. Er wurde validiert für ELISA und IHC (p).
ACTH
Reaktivität: Human, Ratte
IF (p), IF (cc)
Wirt: Kaninchen
Polyclonal
AbBy Fluor® 750
Applikationshinweise
Optimal dilution of the recombinant ACTH antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the recombinant ACTH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
ACTH
(Adrenocorticotropic hormone (ACTH))
Andere Bezeichnung
ACTH
Hintergrund
ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH), does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.