MYCN Antikörper (full length)

Produktnummer ABIN7878702

Der Maus Monoklonal anti-MYCN Antikörper wird verwendet zum Nachweis von MYCN in Proben von Human, Maus und Ratte. Er wurde validiert für WB und IF.

Kurzübersicht für MYCN Antikörper (full length) (ABIN7878702)

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MYCN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: NMYC-1

Produktdetails anti-MYCN Antikörper

Bindungsspezifität: full length

Verwendungszweck: n-Myc Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant full-length human n-Myc protein was used as the immunogen for the n-Myc antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the n-Myc antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the n-Myc antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Andere Bezeichnung: n-Myc

Hintergrund: The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.

UniProt: P04198