IL-10 Antikörper (full length)

Produktnummer ABIN7878456

Der Maus Monoklonal anti-IL-10 Antikörper wird verwendet zum Nachweis von IL-10 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für IL-10 Antikörper (full length) (ABIN7878456)

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-10 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: IL10-8711

Produktdetails anti-IL-10 Antikörper

Bindungsspezifität: full length

Verwendungszweck: Interleukin 10 Antibody / IL-10 (azide and preservative free)

Aufreinigung: Protein A affinity

Immunogen: Recombinant full-length human Interleukin 10 (IL10) protein was used as the immunogen for the Interleukin 10 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Interleukin 10 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Interleukin 10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu IL-10

Target: IL-10 (IL10) (Interleukin 10 (IL10))

Andere Bezeichnung: Interleukin 10

Hintergrund: Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.

UniProt: P22301

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints