CHID1 Antikörper (full length)

Produktnummer ABIN7877976

Der Maus Monoklonal anti-CHID1 Antikörper wird verwendet zum Nachweis von CHID1 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für CHID1 Antikörper (full length) (ABIN7877976)

Target: CHID1 (Chitinase Domain Containing 1 (CHID1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CHID1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: CHID1-6368

Produktdetails anti-CHID1 Antikörper

Bindungsspezifität: full length

Verwendungszweck: SI-CLP Antibody / CHID1 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: Recombinant full-length human SI-CLP protein was used as the immunogen for the CHID1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SI-CLP antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SI-CLP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CHID1

Target: CHID1 (Chitinase Domain Containing 1 (CHID1))

Andere Bezeichnung: SI-CLP

Hintergrund: SI-CLP (stabilin-1 interacting chitinase-like), also known as CHID1 (chitinase domain-containing protein 1), is a 393 amino acid secreted protein that belongs to the glycosyl hydrolase 18 family. SI-CLP interacts with STAB1 and localizes to lysosome in cells of monocytic, T, B and epithelial origin. SI-CLP is a saccharide- and LPS-binding protein with possible roles in pathogen sensing and endotoxin neutralization. Ligand-binding specificity relates to the length of the oligosaccharides, with preference for chitotetraose (in vitro). The SI-CLP protein is up-regulated by IL4/interleukin-4 and dexamethasone in the macrophages, and is also up-regulated by glucocorticoid. Existing as three alternatively spliced isoforms, the SI-CLP gene is conserved in chimpanzee, canine, bovine, mouse, rat, chicken, zebrafish, fruit fly, mosquito, A. thaliana and rice, and maps to human chromosome 11p15.5.

UniProt: Q9BWS9