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Rekombinanter beta Catenin Antikörper (full length)

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch beta Catenin in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.
Produktnummer ABIN7877828
642,40 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen

Kurzübersicht für Rekombinanter beta Catenin Antikörper (full length) (ABIN7877828)

Target

Alle beta Catenin (CATNB) Antikörper anzeigen
beta Catenin (CATNB) (Catenin, beta (CATNB))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 414
  • 275
  • 252
  • 27
  • 23
  • 21
  • 16
  • 16
  • 7
  • 5
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 317
  • 102
  • 2
  • 1
  • 1
Kaninchen

Klonalität

  • 254
  • 167
  • 2
Monoklonal

Konjugat

  • 161
  • 27
  • 11
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 3
  • 3
  • 1
  • 1
  • 1
Dieser beta Catenin Antikörper ist unkonjugiert

Applikation

  • 271
  • 178
  • 145
  • 121
  • 118
  • 116
  • 74
  • 64
  • 53
  • 44
  • 36
  • 32
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse

Carrier-free

Klon

CTNNB1-7044R
  • Bindungsspezifität

    • 54
    • 38
    • 26
    • 22
    • 20
    • 20
    • 19
    • 17
    • 16
    • 16
    • 16
    • 15
    • 10
    • 9
    • 8
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    full length

    Verwendungszweck

    Recombinant Beta Catenin Antibody (azide and preservative free)

    Aufreinigung

    Protein A affinity

    Immunogen

    Recombinant full-length human Beta Catenin protein was used as the immunogen for the recombinant Beta Catenin antibody.

    Isotyp

    IgG, kappa
  • Applikationshinweise

    Optimal dilution of the recombinant Beta Catenin antibody should be determined by the researcher.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Aliquot the recombinant Beta Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • Target

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    Andere Bezeichnung

    Beta Catenin

    Hintergrund

    Beta-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. In normal tissues, beta-catenin is localized to the membrane of epithelial cells, consistent with its role in the cell adhesion complex. In breast ductal neoplasia, beta-catenin is usually localized in cellular membranes. However, in lobular neoplasia, a marked redistribution of beta-catenin throughout the cytoplasm results in a diffuse cytoplasmic pattern. Immuno-staining of beta-catenin and E-cadherin is helps in the accurate identification of ductal and lobular neoplasms, including a distinction between low-grade ductal carcinoma in situ (DCIS) and lobular carcinoma. Additionally, some rectal and gastric adenocarcinomas demonstrate diffuse cytoplasmic beta-catenin staining and a lack of membranous staining, mimicking the staining pattern observed with lobular breast carcinomas.

    UniProt

    P35222

    Pathways

    Peptide Hormone Metabolism
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