IRF5 Antikörper (AA 98-477)

Produktnummer ABIN7877286

Der Kaninchen Polyklonal anti-IRF5 Antikörper wird verwendet zum Nachweis von IRF5 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF und FACS.

Kurzübersicht für IRF5 Antikörper (AA 98-477) (ABIN7877286)

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-IRF5 Antikörper

Bindungsspezifität: AA 98-477

Verwendungszweck: Interferon regulatory factor 5 Antibody / IRF5

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids R98-A477) was used as the immunogen for the Interferon regulatory factor 5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Interferon regulatory factor 5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Interferon regulatory factor 5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu IRF5

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Andere Bezeichnung: Interferon regulatory factor 5

Hintergrund: Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.

UniProt: Q13568

Pathways: TLR Signalweg, Autophagie