Neurexin 1 Antikörper (AA 77-110)

Produktnummer ABIN7876757

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Neurexin 1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für Neurexin 1 Antikörper (AA 77-110) (ABIN7876757)

Target: Neurexin 1 (NRXN1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurexin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Neurexin 1 Antikörper

Bindungsspezifität: AA 77-110

Verwendungszweck: NRXN1 Antibody / Neurexin 1 beta

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 77-110 from the human protein was used as the immunogen for this NRXN1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the NRXN1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4oC for up to one month. For long term, aliquot the NRXN1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Neurexin 1

Target: Neurexin 1 (NRXN1)

Andere Bezeichnung: NRXN1

Hintergrund: Neurexin 1 is primarily known for its role in the formation and maintenance of synapses, the connections between neurons that allow for communication in the brain. It acts as a cell adhesion molecule, helping to guide the development of synapses and ensuring proper signaling between neurons. Studies have shown that mutations in the NRXN1 gene can lead to disruptions in synaptic function, ultimately impacting brain development and function. These mutations have been associated with a variety of neurological disorders, including autism spectrum disorder, schizophrenia, and intellectual disabilities.

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development