Neurexin 1 Antikörper (AA 141-294)

Produktnummer ABIN5693015

Produktdetails anti-Neurexin 1 Antikörper

Target: Neurexin 1 (NRXN1)

Bindungsspezifität: AA 141-294

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurexin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Neurexin 1 detection. Tested with WB, IHC-F, ICC, FCM, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human Neurexin 1 recombinant protein (Position: D141-E294).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(F) and ICC.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu Neurexin 1

Target: Neurexin 1 (NRXN1)

Andere Bezeichnung: NRXN1 (NRXN1 Produkte)

Synonyme: Hs.22998 antikoerper, PTHSL2 antikoerper, SCZD17 antikoerper, CG7050 antikoerper, CT21808 antikoerper, Dmel\\CG7050 antikoerper, Nrx antikoerper, Nrx1 antikoerper, dnrx antikoerper, dnrx-1 antikoerper, nrx antikoerper, Nrxn1b antikoerper, NRXN1 antikoerper, Nrx-1 antikoerper, GB13455 antikoerper, GB18754 antikoerper, 1700062G21Rik antikoerper, 9330127H16Rik antikoerper, A230068P09Rik antikoerper, mKIAA0578 antikoerper, neurexin 1 antikoerper, Neurexin 1 antikoerper, neurexin I antikoerper, neurexin 1b antikoerper, neurexin 1a antikoerper, NRXN1 antikoerper, Nrx-1 antikoerper, Nrxn1 antikoerper, nrxn1 antikoerper, nrxn1b antikoerper, nrxn1a antikoerper

Hintergrund:

Synonyms: Neurexin-1-beta, Neurexin I-beta, NRXN1

Background: Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

UniProt: P58400

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development