Rekombinanter Thyroperoxidase Antikörper (AA 685-804)
Kurzübersicht für Rekombinanter Thyroperoxidase Antikörper (AA 685-804) (ABIN7876422)
Target
Alle Thyroperoxidase (TPO) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 685-804
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Verwendungszweck
- Recombinant TPO Antibody / Thyroid Peroxidase (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A portion of amino acids 685-804 from the human protein was used as the immunogen for the recombinant TPO antibody.
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Isotyp
- IgG
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anti-Thyroid Peroxidase (TPO) (Internal Region) antibody
TPO Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 1-933) antibodyTPO Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 672-779) antibodyTPO Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2A11 unconjugated
anti-Thyroid Peroxidase (TPO) antibodyTPO Reaktivität: Human IHC Wirt: Kaninchen Monoclonal unconjugated
anti-Thyroid Peroxidase (TPO) (C-Term) antibodyVerified TPO Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 111-210) antibodyTPO Reaktivität: Human WB, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (AA 685-804) antibodyTPO Reaktivität: Human IHC Wirt: Kaninchen Monoclonal TPO-3813R unconjugated Recombinant Antibody
anti-Thyroid Peroxidase (TPO) (AA 685-804) antibodyTPO Reaktivität: Human IHC Wirt: Maus Monoclonal TPO-1921 unconjugated
anti-Thyroid Peroxidase (TPO) (AA 107-276) antibodyTPO Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Thyroid Peroxidase (TPO) (C-Term) antibody (Biotin)Verified TPO Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal Biotin
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Applikationshinweise
- Optimal dilution of the recombinant TPO antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Handhabung
- Avoid repeated freeze-thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the recombinant TPO antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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Andere Bezeichnung
- TPO
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Hintergrund
- Thyroperoxidase (TPO) is a 933 amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA.Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors.
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UniProt
- P07202
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Pathways
- Thyroid Hormone Synthesis
Target
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