Integrin Alpha2b Antikörper (AA 675-714)

Produktnummer ABIN7876394

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Integrin Alpha2b in FACS, WB, ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für Integrin Alpha2b Antikörper (AA 675-714) (ABIN7876394)

Target: Integrin Alpha2b (CD41)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Integrin Alpha2b Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Integrin Alpha2b Antikörper

Bindungsspezifität: AA 675-714

Verwendungszweck: ITGA2B Antibody / Integrin alpha 2b

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids A675-R714) was used as the immunogen for the ITGA2B antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ITGA2B antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ITGA2B antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Andere Bezeichnung: ITGA2B

Hintergrund: Integrin alpha-IIb is a protein that in humans is encoded by the ITGA2B gene. It is mapped to 17q21.32. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibrinogen receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

UniProt: P08514

Pathways: Integrin Complex