TLR6 Antikörper (AA 65-553)
Kurzübersicht für TLR6 Antikörper (AA 65-553) (ABIN7876282)
Target
Alle TLR6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 65-553
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Verwendungszweck
- Tlr6 Antibody
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Aufreinigung
- Antigen affinity purified
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Immunogen
- Recombinant mouse protein (amino acids S65-E553) was used as the immunogen for the Tlr6 antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the Tlr6 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the Tlr6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- TLR6 (Toll-Like Receptor 6 (TLR6))
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Andere Bezeichnung
- Tlr6
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Hintergrund
- Toll-like receptor 6 is a protein that in humans is encoded by the TLR6 gene. The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.
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UniProt
- Q9EPW9
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Pathways
- TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Target
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