TLR1 Antikörper (AA 62-404)

Produktnummer ABIN7876164

Der Kaninchen Polyklonal anti-TLR1 Antikörper wird verwendet zum Nachweis von TLR1 in Proben von Human und Ratte. Er wurde validiert für WB, ELISA, FACS und IHC (p).

Kurzübersicht für TLR1 Antikörper (AA 62-404) (ABIN7876164)

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TLR1 Antikörper

Bindungsspezifität: AA 62-404

Verwendungszweck: Toll-like Receptor 1 Antibody / TLR1

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids T62-D404) was used as the immunogen for the Toll-like Receptor 1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Toll-like Receptor 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Toll-like Receptor 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TLR1

Target: TLR1 (Toll-Like Receptor 1 (TLR1))

Andere Bezeichnung: Toll-like Receptor 1

Hintergrund: Toll-like receptor 1 (TLR1), also called TIL or CD281 is a member of the Toll-like receptor family (TLR) of pattern recognition receptors of the innate immune system. This gene is mapped to 4p14 by fluorescence in situ hybridization. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.

UniProt: Q15399

Pathways: TLR Signalweg, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades