alpha 2 Macroglobulin Antikörper (AA 604-748)

Produktnummer ABIN7876076

Dieser Maus Monoklonal Antikörper detektiert spezifisch alpha 2 Macroglobulin in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für alpha 2 Macroglobulin Antikörper (AA 604-748) (ABIN7876076)

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser alpha 2 Macroglobulin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: A2M-3622

Produktdetails anti-alpha 2 Macroglobulin Antikörper

Bindungsspezifität: AA 604-748

Verwendungszweck: Alpha-2-M Antibody / Alpha-2-Macroglobulin / A2M (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A portin of amino acids 604-748 from the human protein was used as the immunogen for the Alpha-2-M antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Alpha-2-M antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Alpha-2-M antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Andere Bezeichnung: Alpha-2-M

Hintergrund: A2-Macroglobulin acts as an antiprotease and is able to inactivate an enormous variety of proteinases. It functions as an inhibitor of fibrinolysis by inhibiting plasmin and kallikrein. It functions as an inhibitor of coagulation by inhibiting thrombin. A2-macroglobulin may act as a carrier protein because it also binds to numerous growth factors and cytokines, such as platelet-derived growth factor, basic fibroblast growth factor, TGF-b, insulin, and IL-1b. [UniProt]

UniProt: P01023

Pathways: Lipid Metabolism