Rekombinanter CD35 Antikörper (AA 600-900)

Produktnummer ABIN7876035

Der Kaninchen Monoklonal anti-CD35 Antikörper wird verwendet zum Nachweis von CD35 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter CD35 Antikörper (AA 600-900) (ABIN7876035)

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CD35 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CR1-8833R

Produktdetails anti-CD35 Antikörper

Bindungsspezifität: AA 600-900

Verwendungszweck: Complement receptor 1 Antibody / CD35

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 600-900) from the human protein was used as the immunogen for the Complement receptor 1 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Complement receptor 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Complement receptor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CD35

Target: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Andere Bezeichnung: Complement receptor 1

Hintergrund: CD35, complement receptor 1, is a cell membrane-bound, monomeric glycoprotein on numerous cell types including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils, and neutrophils. Anti-CD35 is considered a mature B-cell marker which labels follicular dendritic reticulum cells and tumors derived from such cells such as follicular dendritic cell tumor/sarcoma.

UniProt: P17927

Pathways: Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity