CD35 Antikörper
Kurzübersicht für CD35 Antikörper (ABIN7073563)
Target
Alle CD35 (CR1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Maus, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Human CD35
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Applikationshinweise
- WB (M,R) 1:500-1:1000, IHC/IF (H,R) 1:650-1:1300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
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Andere Bezeichnung
- CD35
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Hintergrund
- This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis.
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Molekulargewicht
- 224 kDa
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Gen-ID
- 1378
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NCBI Accession
- NP_000564
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UniProt
- P17927
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Pathways
- Komplementsystem, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
Target
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