APOB Antikörper (AA 592-689)

Produktnummer ABIN7875923

Dieser Maus Monoklonal Antikörper detektiert spezifisch APOB in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für APOB Antikörper (AA 592-689) (ABIN7875923)

Target: APOB (Apolipoprotein B (APOB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser APOB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: APOB-4333

Produktdetails anti-APOB Antikörper

Bindungsspezifität: AA 592-689

Verwendungszweck: Apolipoprotein B Antibody / APOB (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A portion of amino acids 592-689 from the human protein was used as the immunogen for the Apolipoprotein B antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Apolipoprotein B antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the Apolipoprotein B antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu APOB

Target: APOB (Apolipoprotein B (APOB))

Andere Bezeichnung: Apolipoprotein B

Hintergrund: Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by APOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the resultof RNA editing of a common apoB gene.

UniProt: P04114

Pathways: Lipid Metabolism