APOB Antikörper (Apolipoprotein B)

Details for Product anti-APOB Antibody No. ABIN968961
Antigen
  • FLDB
  • LDLCQ4
  • Ac1-060
  • Apo B-100
  • ApoB-100
  • ApoB-48
  • AI315052
  • apob-100
  • apob-48
  • APOB-100
  • ApoB(100)
  • APOB
  • apolipoprotein B
  • APOB
  • Apob
Reaktivität
Human
334
45
36
11
4
1
1
Wirt
Maus
150
105
104
6
4
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser APOB Antikörper ist unkonjugiert
33
28
17
13
13
12
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunocytochemistry (ICC), Flow Cytometry (FACS), ELISA, Western Blotting (WB)
212
155
78
73
44
22
20
19
17
17
16
14
13
6
3
2
2
1
1
1
1
1
1
Optionen
Immunogen Purified recombinant fragment of human ApoB expressed in E. Coli.
Klon 6G6
Isotyp IgG1
Reinigung Ascites
Plasmids, Primers & others Plasmide, Primers & weitere APOB products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung ApoB (APOB Antibody Abstract)
Hintergrund This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels.
Molekulargewicht 516 kDa
Gen-ID 338
HGNC 338
Pathways Lipid Metabolism
Applikations-hinweise ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C,-20 °C
Informationen zur Lagerung 4°C, -20°C for long term storage
Bilder des Herstellers
Image no. 1 for anti-Apolipoprotein B (APOB) antibody (ABIN968961) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Image no. 2 for anti-Apolipoprotein B (APOB) antibody (ABIN968961) Figure 3: Immunofluorescence analysis of HepG2 cells using ApoB mouse mAb (green) . B...
Image no. 3 for anti-Apolipoprotein B (APOB) antibody (ABIN968961) Figure 4: Western blot analysis using ApoB mAb against human ApoB (AA: 3900-4110) rec...
Image no. 4 for anti-Apolipoprotein B (APOB) antibody (ABIN968961) Figure 2: Flow cytometric analysis of serun using ApoB mouse mAb (green) and negative...
Produkt verwendet in: Benn: "Apolipoprotein B levels, APOB alleles, and risk of ischemic cardiovascular disease in the general population, a review." in: Atherosclerosis, Vol. 206, Issue 1, pp. 17-30, 2009 (PubMed).

Peterson, Mack, Hall, Alsup, Alexander, Sully, Sawires, Cheung, Otto, Gresham: "Apolipoprotein B Is an innate barrier against invasive Staphylococcus aureus infection." in: Cell host & microbe, Vol. 4, Issue 6, pp. 555-66, 2008 (PubMed).

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