Der Maus Monoklonal anti-APOB Antikörper (Klon APOB-4335) (ABIN7875919) detektiert spezifisch APOB in IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
APOB
Reaktivität: Human
WB
Wirt: Maus
Monoclonal
C3
unconjugated
Applikationshinweise
Optimal dilution of the Apolipoprotein B antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Apolipoprotein B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
APOB
(Apolipoprotein B (APOB))
Andere Bezeichnung
APOB
Hintergrund
Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by APOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the result of RNA editing of a common apoB gene.