EPH Receptor A3 Antikörper (AA 59-514)

Produktnummer ABIN7875906

Der Kaninchen Polyklonal anti-EPH Receptor A3 Antikörper wird verwendet zum Nachweis von EPH Receptor A3 in Proben von Human. Er wurde validiert für WB, ELISA, IHC (p), IF und FACS.

Kurzübersicht für EPH Receptor A3 Antikörper (AA 59-514) (ABIN7875906)

Target: EPH Receptor A3 (EPHA3)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-EPH Receptor A3 Antikörper

Bindungsspezifität: AA 59-514

Verwendungszweck: Eph receptor A3 Antibody / EphA3

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D59-A514) was used as the immunogen for the Eph receptor A3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Eph receptor A3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Eph receptor A3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu EPH Receptor A3

Target: EPH Receptor A3 (EPHA3)

Andere Bezeichnung: Eph receptor A3

Hintergrund: Ephrin Receptor EphA3, is also known as human embryo kinase(HEK) or Eph-like tyrosine kinase1(ETK1). Kinases that phosphorylate proteins on tyrosine residues(protein tyrosine kinases, PTKs), such as EPHA3, form a structurally related group of molecules that exhibit functional diversity. Genetic alterations that lead to the inappropriate activation or expression of PTKs may be oncogenic. Many growth factor receptors are PTKs, e.g., the receptors for epidermal growth factor(EGFR), platelet-derived growth factor(PDGFR1,PDGFR2), colony-stimulating factor-1(CSF1R), and stem cell growth factor. The EPHA3 gene is mapped to 3p11.2. Sequence comparison with other PTKs showed a high degree of homology with members of the EPH and ELK(EPHB1) families of receptor tyrosine kinases. Within axial nerves, establishment of discrete afferent and efferent pathways depends on coordinate signaling between coextending sensory and motor projections.

UniProt: P29320

Pathways: RTK Signalweg, Regulation of Cell Size