EPH Receptor A3 Antikörper (AA 751-983)
Kurzübersicht für EPH Receptor A3 Antikörper (AA 751-983) (ABIN969101)
Target
Alle EPH Receptor A3 (EPHA3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 751-983
-
Verwendungszweck
- EphA3 Antibody
-
Aufreinigung
- Ascitic fluid
-
Immunogen
- Purified recombinant fragment of EphA3 (aa751-983) expressed in E. Coli.
-
Isotyp
- IgG2b
-
-
-
-
Applikationshinweise
- ELISA: 1/10000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Ascitic fluid containing 0.03 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
-
: "Adam meets Eph: an ADAM substrate recognition module acts as a molecular switch for ephrin cleavage in trans." in: Cell, Vol. 123, Issue 2, pp. 291-304, (2005) (PubMed).
-
-
- EPH Receptor A3 (EPHA3)
-
Andere Bezeichnung
- EphA3
-
Hintergrund
- EphA3: EPH receptor A3. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene.
-
UniProt
- P54764
-
Pathways
- RTK Signalweg, Regulation of Cell Size
Target
-