Rekombinanter alpha Sarcomeric Actin (AA 557-692) Antikörper

Produktnummer ABIN7875745

Der Kaninchen Monoklonal anti-alpha Sarcomeric Actin Antikörper (Klon ACTN2-7041R) (ABIN7875745) detektiert spezifisch alpha Sarcomeric Actin in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter alpha Sarcomeric Actin (AA 557-692) Antikörper (ABIN7875745)

Target: alpha Sarcomeric Actin

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: ACTN2-7041R

Produktdetails

Bindungsspezifität: AA 557-692

Verwendungszweck: Recombinant Sarcomeric Alpha Actinin Antibody / Alpha Actinin 2 / ACTN2 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 557-692 from the human protein was used as the immunogen for the recombinant Sarcomeric Alpha Actinin antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Sarcomeric Alpha Actinin antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Handhabung: Avoid repeated freeze-thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant Sarcomeric Alpha Actinin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: alpha Sarcomeric Actin

Andere Bezeichnung: Sarcomeric Alpha Actinin

Hintergrund: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

UniProt: P35609