alpha Sarcomeric Actin Antikörper
Kurzübersicht für alpha Sarcomeric Actin Antikörper (ABIN7075510)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- KLH conjugated Synthetic peptide corresponding to Mouse alpha Actinin 2
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Applikationshinweise
- WB (M,R) 1:2000, IHC/IF ,IEM (M,R) 1:500-1:1000/1:2000/1:50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- alpha Sarcomeric Actin
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Andere Bezeichnung
- Sarcomeric Alpha Actinin
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Hintergrund
- The primary function of alpha-actinin 2 is to crosslink filamentous actin molecules and titin molecules from adjoining sarcomeres at Z-discs, a function that is modulated by phospholipids. It is clear from studies by Hampton etal. that this crosslinking can assume a variety of conformations, with preferences for 60° and 120° angles. Alpha-actinin 2 also functions in docking signaling molecules at Z-discs, and additional studies have also implicated alpha-actinin 2 in the binding of cardiac ion channels, Kv1.5 in particular.
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Molekulargewicht
- 104 kDa
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Gen-ID
- 11472
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NCBI Accession
- NP_150371
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UniProt
- Q9JI91
Target
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