SOX18 Antikörper (AA 50-250)

Produktnummer ABIN7875394

Der Maus Monoklonal anti-SOX18 Antikörper (Klon SOX18-3271) (ABIN7875394) detektiert spezifisch SOX18 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SOX18 Antikörper (AA 50-250) (ABIN7875394)

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOX18 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: SOX18-3271

Produktdetails anti-SOX18 Antikörper

Bindungsspezifität: AA 50-250

Verwendungszweck: SOX18 Antibody

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant human SOX18 protein fragment (within amino acids 50-250) was used as the immunogen for the SOX18 antibody.

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SOX18 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the SOX18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu SOX18

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Andere Bezeichnung: SOX18

Hintergrund: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNAbinding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.

UniProt: P35713