SOX18 Antikörper (AA 50-250)

Produktnummer ABIN7860273

Der Maus Monoklonal anti-SOX18 Antikörper wird verwendet zum Nachweis von SOX18 in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für SOX18 Antikörper (AA 50-250) (ABIN7860273)

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SOX18 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: SOX18-3271

Produktdetails anti-SOX18 Antikörper

Bindungsspezifität: AA 50-250

Verwendungszweck: SOX18 Antibody

Spezifität: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNAbinding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Sox-18 is a 384 amino acid nuclear protein that contains one HMG box DNA-binding domain and belongs to the Sox family of transcriptional regulators.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human SOX18 protein fragment (around aa 50-250) (exact sequence is proprietary)

Isotyp: IgG2, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu SOX18

Target: SOX18 (SRY (Sex Determining Region Y)-Box 18 (SOX18))

Andere Bezeichnung: SOX18

Hintergrund:

HLTS, SOX 18, SRY (sex determining region Y) box 18, SRY box 18, Transcription factor SOX-18

Human heart|kidney|skin or endometrium.

Molekulargewicht: 45kDa

Gen-ID: 54345, 8619

UniProt: P35713