Fibronectin 1 Antikörper (AA 467-595)
Kurzübersicht für Fibronectin 1 Antikörper (AA 467-595) (ABIN7875151)
Target
Alle Fibronectin 1 (FN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 467-595
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Verwendungszweck
- Fibronectin 1 Antibody / FN1 (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A portion of amino acids 467-595 was used as the immunogen for the Fibronectin 1 antibody.
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal dilution of the Fibronectin 1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Fibronectin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Fibronectin 1 (FN1)
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Andere Bezeichnung
- Fibronectin 1
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Hintergrund
- Fibronectins are disulfide-linked, dimeric glycoproteins of ~440 kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.
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UniProt
- P02751
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagie
Target
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