PRR5 Antikörper (AA 45-366)

Produktnummer ABIN7875069

Der Kaninchen Polyklonal anti-PRR5 Antikörper wird verwendet zum Nachweis von PRR5 in Proben von Human. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für PRR5 Antikörper (AA 45-366) (ABIN7875069)

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRR5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-PRR5 Antikörper

Bindungsspezifität: AA 45-366

Verwendungszweck: Protor-1 Antibody / Protein observed with Rictor-1 / PRR5

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids S45-D366) was used as the immunogen for the Protor-1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Protor-1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Protor-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PRR5

Target: PRR5 (Proline Rich 5 (Renal) (PRR5))

Andere Bezeichnung: Protor-1

Hintergrund: This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2), and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist, which led to the original description of PRR5 and ARHGAP8 being a single gene.

UniProt: P85299

Pathways: PI3K-Akt Signalweg