Rekombinanter SMAD4 Antikörper (AA 400-552)
Kurzübersicht für Rekombinanter SMAD4 Antikörper (AA 400-552) (ABIN7874727)
Target
Alle SMAD4 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 400-552
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Verwendungszweck
- SMAD4 Antibody
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant partial protein sequence (within amino acids 400-552) from the human protein was used as the immunogen for the SMAD4 antibody.
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Isotyp
- IgG, kappa
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anti-SMAD Family Member 4 (SMAD4) (N-Term) antibody
SMAD4 Reaktivität: Human WB, IP, CUT&RUN Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 1-552) antibodySMAD4 Reaktivität: Human WB, ELISA, IF, PLA Wirt: Maus Monoclonal 3E2 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 255-284) antibodySMAD4 Reaktivität: Human, Maus WB, IF Wirt: Kaninchen Polyclonal RB14714 unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodySMAD4 Reaktivität: Human, Maus WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 4G1C6 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 400-428) antibodySMAD4 Reaktivität: Human WB, IHC, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 27-195) antibodySMAD4 Reaktivität: Human WB, IHC, ELISA, IP Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodyKD Validated SMAD4 Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 23GB975 unconjugated Recombinant Antibody
anti-SMAD Family Member 4 (SMAD4) (AA 400-428), (C-Term) antibodySMAD4 Reaktivität: Human WB, IF, IHC (p), FACS Wirt: Kaninchen Polyclonal RB20720 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 40-120) antibodySMAD4 Reaktivität: Human, Maus, Ratte, Affe WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (pThr277) antibodySMAD4 Reaktivität: Human IHC, ELISA, IF, DB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal dilution of the SMAD4 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Aliquot the SMAD4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- SMAD4 (SMAD Family Member 4 (SMAD4))
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Andere Bezeichnung
- SMAD4
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Hintergrund
- SMAD4 is implicated as a tumor suppressor since it is inactivated in more than half of pancreatic carcinomas and to a lesser extent in a variety of other cancers. The lack of SMAD4 expression is present in approximately 80 % of cases of pancreatic adenocarcinoma, but rarely in endometrial (0 %), colorectal (0 %), ovarian (3 %), lung (0 %), breast (2 %) adenocarcinomas, and malignant melanoma (4 %). SMAD4is an important marker for confirming a diagnosis of pancreatic adenocarcinoma.
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UniProt
- Q13485
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Pathways
- Zellzyklus, Chromatin Binding, Autophagie
Target
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