PKM Antikörper (AA 383-417)

Produktnummer ABIN7874526

Der Kaninchen Polyklonal anti-PKM Antikörper wird verwendet zum Nachweis von PKM in Proben von Human. Er wurde validiert für WB, FACS und IHC (p).

Kurzübersicht für PKM Antikörper (AA 383-417) (ABIN7874526)

Target: PKM (Pyruvate Kinase M1/2 (PKM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PKM Antikörper

Bindungsspezifität: AA 383-417

Verwendungszweck: Pyruvate Kinase PKM Antibody / PKM2

Aufreinigung: Purified

Immunogen: A portion of amino acids 383-417 from the human protein was used as the immunogen for the Pyruvate Kinase PKM antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Pyruvate Kinase PKM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Pyruvate Kinase PKM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu PKM

Target: PKM (Pyruvate Kinase M1/2 (PKM))

Andere Bezeichnung: Pyruvate Kinase PKM

Hintergrund: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

UniProt: P14618

Pathways: Warburg Effekt