MSH6 Antikörper (AA 374-540)
Kurzübersicht für MSH6 Antikörper (AA 374-540) (ABIN7874459)
Target
Alle MSH6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 374-540
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Verwendungszweck
- MSH6 Antibody
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Aufreinigung
- Protein G affinity chromatography
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Immunogen
- A portion of amino acids 374-540 from the human protein were used as the immunogen for this MSH6 antibody.
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Isotyp
- IgG2b, kappa
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anti-MutS Homolog 6 (E. Coli) (MSH6) antibody
MSH6 Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 3E1 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 2E3A10 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 7D9H5 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 931-1030) antibodyMSH6 Reaktivität: Human WB, IF, ELISA, PLA Wirt: Maus Monoclonal 1F2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 374-540) antibodyMSH6 Reaktivität: Human WB, IHC, IF, ELISA Wirt: Maus Monoclonal MSH6-3091 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 217-395) antibodyMSH6 Reaktivität: Human, Maus, Affe WB, ELISA, FACS Wirt: Maus Monoclonal 1D1C2 unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (N-Term) antibodyMSH6 Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Pferd, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (Internal Region) antibodyMSH6 Reaktivität: Human, Maus, Ratte WB, IHC, IF, ELISA, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 1310-1360) antibodyMSH6 Reaktivität: Human WB, IHC, FACS, ICC, IP Wirt: Kaninchen Monoclonal BLR117H unconjugated Recombinant Antibody
anti-MutS Homolog 6 (E. Coli) (MSH6) (AA 225-333) antibodyMSH6 Reaktivität: Human, Maus, Ratte, Hund WB, IF Wirt: Maus Monoclonal 44-MSH6 unconjugated
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Applikationshinweise
- Optimal dilution of the MSH6 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store the MSH6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Andere Bezeichnung
- MSH6
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Hintergrund
- The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.
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UniProt
- P52701
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Pathways
- DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
Target
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