Cadherin-16 Antikörper (AA 371-507)

Produktnummer ABIN7874426

Dieser Maus Monoklonal Antikörper detektiert spezifisch Cadherin-16 in ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Cadherin-16 Antikörper (AA 371-507) (ABIN7874426)

Target: Cadherin-16 (CDH16)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cadherin-16 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CDH16-2448

Produktdetails anti-Cadherin-16 Antikörper

Bindungsspezifität: AA 371-507

Verwendungszweck: CDH16 Antibody / Cadherin 16

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 371-507) was used as the immunogen for the CDH16 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CDH16 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the CDH16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu Cadherin-16

Target: Cadherin-16 (CDH16)

Andere Bezeichnung: CDH16

Hintergrund: This MAb recognizes a protein of 130 kDa, identified as Ksp-cadherin (also called CDH16 and Cadherin 16). Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.

UniProt: O75309