CD70 Antikörper (AA 36-191)

Produktnummer ABIN7874303

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CD70 in WB, ELISA und IHC (p). Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.

Kurzübersicht für CD70 Antikörper (AA 36-191) (ABIN7874303)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD70 Antikörper

Bindungsspezifität: AA 36-191

Verwendungszweck: Cd70 Antibody

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant mouse Cd70 protein (amino acids C36-Q191) was used as the immunogen for the Cd70 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Cd70 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Cd70 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: Cd70

Hintergrund: CD70 (Cluster of Differentiation 70) is a protein that in humans is encoded by CD70 gene. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

UniProt: O55237

Pathways: Cancer Immune Checkpoints